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Chiara La Morgia Selected Research

idebenone

1/2021Therapeutic Options in Hereditary Optic Neuropathies.
1/2020Idebenone increases chance of stabilization/recovery of visual acuity in OPA1-dominant optic atrophy.
12/2017International Consensus Statement on the Clinical and Therapeutic Management of Leber Hereditary Optic Neuropathy.
2/2013Idebenone treatment in patients with OPA1-mutant dominant optic atrophy.
9/2011Idebenone treatment in Leber's hereditary optic neuropathy.

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Chiara La Morgia Research Topics

Disease

22Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy)
01/2022 - 12/2006
14Optic Nerve Diseases (Optic Neuropathy)
01/2021 - 01/2007
11Mitochondrial Diseases (Mitochondrial Disease)
01/2021 - 08/2010
10Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy)
01/2021 - 05/2009
9Optic Atrophy
01/2022 - 02/2008
5Ganglion Cysts (Ganglion)
01/2022 - 09/2014
5MELAS Syndrome (Syndrome, MELAS)
01/2021 - 05/2009
4Stroke (Strokes)
01/2022 - 05/2009
4Neurodegenerative Diseases (Neurodegenerative Disease)
01/2022 - 01/2017
4Alzheimer Disease (Alzheimer's Disease)
01/2021 - 01/2016
4Chronic Progressive External Ophthalmoplegia (Progressive External Ophthalmoplegia)
01/2018 - 02/2008
4Mitochondrial Myopathies (Mitochondrial Myopathy)
01/2018 - 02/2008
4Deafness (Deaf Mutism)
07/2015 - 02/2008
3Lactic Acidosis
01/2022 - 05/2009
3Wolfram Syndrome (Syndrome, Wolfram)
01/2022 - 01/2020
3Parkinson Disease (Parkinson's Disease)
01/2022 - 01/2017
3Mitochondrial Encephalomyopathies (Mitochondrial Encephalomyopathy)
01/2022 - 05/2014
3Parkinsonian Disorders (Parkinsonism)
01/2018 - 07/2015
2Narcolepsy
01/2022 - 06/2014
2Leigh Disease (Leigh's Disease)
01/2022 - 05/2014
2Atrophy
01/2021 - 01/2012
2Brain Diseases (Brain Disorder)
01/2021 - 01/2021
2Dementia (Dementias)
01/2021 - 07/2015
2Hereditary Spastic Paraplegia
06/2020 - 05/2009
2Cataplexy
01/2020 - 06/2014
2Ataxia (Dyssynergia)
01/2020 - 02/2008
2Cataract (Cataracts)
08/2014 - 05/2009
1Overweight
01/2022
1Hypertriglyceridemia
01/2022
1COVID-19
01/2021
1Myoclonic Epilepsies (Myoclonic Encephalopathy)
10/2020
1Status Epilepticus (Complex Partial Status Epilepticus)
10/2020
1Spinocerebellar ataxia 28
06/2020
1Hereditary Sensory and Autonomic Neuropathy Type Ie
01/2020
1Epilepsy (Aura)
01/2020
1Macular Degeneration (Age-Related Maculopathy)
01/2020
1Seizures (Absence Seizure)
01/2020
1Renal Insufficiency (Renal Failure)
01/2020
1Sleepiness
01/2018
1Hearing Loss (Hearing Impairment)
01/2016
1Cognitive Dysfunction
07/2015
1Peripheral Nervous System Diseases (PNS Diseases)
07/2015
1Auditory neuropathy
03/2015
1Deglutition Disorders (Dysphagia)
08/2014
1Muscular Diseases (Myopathy)
08/2014
1Persistent Vegetative State (Vegetative State)
06/2014
1Cerebellar Ataxia, Deafness, and Narcolepsy
05/2014
1Calcinosis
08/2011
1Blindness (Hysterical Blindness)
02/2011
1Glaucoma
01/2011
1Seasonal Affective Disorder
01/2011
1Photophobia (Light Sensitivity)
01/2011

Drug/Important Bio-Agent (IBA)

26Mitochondrial DNA (mtDNA)IBA
01/2022 - 12/2006
18Retinaldehyde (Retinal)IBA
01/2022 - 10/2011
8melanopsinIBA
01/2022 - 08/2010
5idebenoneIBA
01/2021 - 09/2011
5Biomarkers (Surrogate Marker)IBA
01/2021 - 11/2018
3Pharmaceutical PreparationsIBA
01/2021 - 12/2016
3Lactic Acid (Lactate)FDA LinkGeneric
01/2021 - 08/2010
3CalciumIBA
06/2020 - 08/2011
3DNA (Deoxyribonucleic Acid)IBA
01/2020 - 01/2017
2OrexinsIBA
01/2022 - 06/2014
2MethyltransferasesIBA
01/2020 - 01/2020
2Glutamic Acid (Glutamate)FDA Link
01/2020 - 05/2009
2Electron Transport Complex I (NADH-CoQ Reductase)IBA
01/2017 - 02/2011
2MelatoninIBA
06/2014 - 08/2010
1HDL CholesterolIBA
01/2022
1NADH DehydrogenaseIBA
01/2022
1Anti-Bacterial Agents (Antibiotics)IBA
01/2021
1Alanine (L-Alanine)FDA Link
01/2021
1Biological ProductsIBA
01/2021
1GlucocorticoidsIBA
01/2021
1Azithromycin (Zithromax)FDA LinkGeneric
01/2021
1Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA
01/2021
1AntioxidantsIBA
01/2021
1salicylhydroxamic acid (SHAM)IBA
12/2020
1fibroblast growth factor 21IBA
10/2020
1Growth Differentiation Factor 15IBA
10/2020
1Transfer RNA (tRNA)IBA
10/2020
1m-AAA proteasesIBA
06/2020
1Levetiracetam (Keppra)FDA LinkGeneric
01/2020
1purineIBA
01/2020
1Adenosine Triphosphatases (ATPase)IBA
01/2020
1Anticonvulsants (Antiepileptic Drugs)IBA
01/2020
1Arginine (L-Arginine)FDA Link
01/2020
1Urea (Carbamide)FDA LinkGeneric
01/2020
1Dopamine (Intropin)FDA LinkGeneric
11/2018
1SuspensionsIBA
01/2018
1Membrane Proteins (Integral Membrane Proteins)IBA
12/2016
1Proteins (Proteins, Gene)FDA Link
08/2015
1Cytochromes b (Cytochrome b)IBA
08/2014
1DNA (Cytosine-5-)-Methyltransferases (DNA (Cytosine 5) Methyltransferase)IBA
05/2014
1Carisoprodol (Soma)FDA LinkGeneric
01/2012
1Phosphorus (Red Phosphorus)IBA
01/2011

Therapy/Procedure

5Therapeutics
01/2021 - 02/2011
1Lasers (Laser)
01/2022
1Intravitreal Injections
12/2020
1Transplantation
01/2020
1Phototherapy (Light Therapy)
01/2017
1Cochlear Implantation
03/2015